1 Features
• Integrated signal chains for Bio-Z, EDA, ECG,
PPG
• Synchronized ECG, PPG enables PTT-based BP
• Bio-Z signal acquisition:
– Multi-frequency Body impedance Analysis with
frequency programmable up to 250kHz
– Low frequency excitation mode for EDA/GSR
– Complex (I, Q). Tetrapolar impedance
measurement
– Sine-wave excitation with a 7-bit DAC
– Calibration scheme to compensate for
electrode impedance and achieve accurate
BioZ
• ECG signal acquisition:
– 1-lead ECG signal acquisition up to 4kHz
– Mode to configure as 2-channel ECG
– INA gain programmable from 1.27 - 12.23
– RLD output to set body bias through the third
electrode
– Input noise (0.5-150Hz): 0.5μVrms at gain of
12.23
– >1GΩ input impedance, CMRR>100dB
– Integrated 370 Hz anti-aliasing low pass filter
– AC, DC lead-off detect: 1.6nA to 1μA
• PPG signal acquisition:
– Acquisition of 24 PPG signal sets (LED, AMB)
– Supports PPG sensors at different data rates
– Peak system SNR of 115 dB in 0.5-10Hz band
enables high-accuracy SpO2 measurement
– Low Current for Continuous Operation with a
Typical Value: 19μA for the Receiver
• PPG Transmitter:
– 8-Bit Programmable LED Current with a range
adjustable from 50mA to 300mA
– LED Short Detection
– Support of 16 LEDs in Common Anode
configuration for SpO2, OHRM, Spectroscopy
• PPG Receiver:
– Supports 5 PDs, 4 parallel receive paths
– Noise filtering with programmable bandwidth
– Trans-impedance Gain: 3.7kΩ to 1MΩ
– 8-bit Ambient Offset Subtraction DAC up to
256μA
– 9-bit LED Offset Subtraction DAC up to 64μA
– Digital Ambient Subtraction at ADC Output
• EDA Signal Acquisition:
– Low-power continuous EDA and PPG
acquisition using the ECG receiver
– Independent data rates for EDA and PPG
acquisition with optimized power cycling
– High-accuracy EDA signal chain for spot-check
EDA using the BIA signal chain
• Supports external clock and internal oscillator
• Option to operate 2 AFEs in parallel
• Option to configure the 5th PD input as a general
purpose voltage measurement channel
• FIFO with 384-sample Depth, SPI™
• Supplies: RX,:1.7-1.9V, I/O: 1.15-1.9V, TX:3-5.5V

2 Applications
• Bio-Z, ECG, PPG, EDA on wearable devices
• Impedance spectroscopy
• Weight scales with body composition
• Current, voltage, impedance sensing

3 Description
The AFE4510 is a versatile signal acquisition system
that supports acquiring PPG, EDA, ECG, and Bioimpedance
signals. A PPG signal chain comprises a
current driver for LEDs and a receiver that senses
the signal from PDs. An ECG receiver with a Rightleg
drive (RLD) can acquire a single-lead ECG from
a pair of electrodes. An impedance measurement
signal chain with integrated excitation & sense can be
used for applications like BIA, EDA, and Impedance
spectroscopy. The outputs of the various signal chains
are digitized by a common ADC and stored in a FIFO
which can be read out using an SPI interface